Description
DICLOMOL SR TABS 100MG 100’S are sustained-release tablets combining the potent anti-inflammatory effects of diclofenac sodium with the analgesic and antipyretic properties of paracetamol (acetaminophen). This formulation is designed to provide prolonged relief from pain and inflammation, improving patient compliance by reducing dosing frequency.
Active Ingredients:
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Diclofenac Sodium 100mg (sustained-release)
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Paracetamol (Acetaminophen)
Indications:
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Management of moderate to severe pain associated with musculoskeletal disorders such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis
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Relief of inflammatory conditions, including postoperative and traumatic pain
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Treatment of fever and other conditions requiring both analgesic and anti-inflammatory effects
Mechanism of Action:
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Diclofenac Sodium: Inhibits cyclooxygenase enzymes COX-1 and COX-2, leading to decreased production of prostaglandins responsible for pain, swelling, and inflammation. The sustained-release formulation ensures gradual and prolonged drug release, maintaining therapeutic levels over an extended period.
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Paracetamol: Acts centrally to reduce pain and fever by inhibiting prostaglandin synthesis, complementing the peripheral action of diclofenac.
Dosage & Administration:
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Typically administered orally, one tablet twice daily or as directed by a healthcare professional
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Should be taken with food or milk to reduce gastrointestinal irritation
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Swallow tablets whole; do not crush or chew to maintain sustained-release properties
Precautions:
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Use cautiously in patients with liver or kidney impairment, gastrointestinal disorders, cardiovascular diseases, or hypersensitivity to NSAIDs
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Not recommended during pregnancy and breastfeeding unless advised by a physician
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Avoid concurrent use with other NSAIDs or paracetamol-containing products without medical supervision
Side Effects:
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May cause gastrointestinal discomfort, nausea, or abdominal pain
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Risk of allergic reactions or skin rash in sensitive individuals
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Prolonged use may increase risk of gastrointestinal bleeding, cardiovascular events, or liver toxicity
DICLOMOL SR TABS 100MG 100’S provide effective, sustained pain relief and anti-inflammatory action, offering a convenient dosing schedule for enhanced patient adherence and improved quality of life.
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