Description
AMOXICLAV (ACINET) 375MG TABLETS 10’S GALAXY
Amoxiclav (Acinet) 375mg Tablets are a combination antibiotic containing 250 mg of amoxicillin and 125 mg of clavulanic acid per tablet. This formulation is designed to treat a broad spectrum of bacterial infections by combining a penicillin-class antibiotic with a beta-lactamase inhibitor.
🔹 Mechanism of Action
- Amoxicillin: A penicillin-class antibiotic that inhibits bacterial cell wall synthesis, leading to cell death.
- Clavulanic Acid: A beta-lactamase inhibitor that protects amoxicillin from degradation by certain resistant bacteria, thereby enhancing its effectiveness.
🔹 Indications
Amoxiclav 375mg Tablets are commonly prescribed for:
- Upper Respiratory Tract Infections: Including tonsillitis, sinusitis, and otitis media.
- Lower Respiratory Tract Infections: Such as acute exacerbation of chronic bronchitis and pneumonia.
- Urinary Tract Infections: Including cystitis, urethritis, and pyelonephritis.
- Skin and Soft Tissue Infections: Such as boils, abscesses, cellulitis, and wound infections.
- Bone and Joint Infections: Including osteomyelitis.
- Dental Infections: Such as dentoalveolar abscesses.(Optum Health Pharmacy)
🔹 Dosage and Administration
- Dosage: Typically, one tablet (375 mg) taken three times a day, preferably every 8 hours, for a maximum of 14 days. For more severe infections, one 625 mg tablet may be taken three times a day.
- Administration: Take with meals to enhance absorption and reduce gastrointestinal side effects.
- Duration: Follow the healthcare provider’s instructions regarding the duration of treatment.(Drugs.com)
🔹 Side Effects
Common side effects may include:
- Gastrointestinal: Nausea, vomiting, diarrhea, or abdominal pain.
- Allergic Reactions: Rash, itching, or swelling.
- Hematologic: Changes in blood cell counts, such as eosinophilia or thrombocytopenia.
- Hepatic: Elevations in liver enzymes; rare cases of jaundice.
Serious side effects are uncommon but may include:
- Severe Allergic Reactions: Anaphylaxis, characterized by difficulty breathing, swelling of the face or throat, and dizziness.
- Severe Diarrhea: Possibly due to Clostridium difficile infection.
If any of these serious side effects occur, seek immediate medical attention.(WebMD)
🔹 Precautions
- Allergy: Contraindicated in patients with a known allergy to penicillin or clavulanic acid.
- Liver or Kidney Impairment: Use with caution; dosage adjustments may be necessary.
- Pregnancy & Breastfeeding: Consult a healthcare provider before use during pregnancy or while breastfeeding.
- Drug Interactions: Inform the healthcare provider of all other medications being taken, as interactions may occur.
🔹 Storage
- Conditions: Store in a cool, dry place, away from direct sunlight.
- Keep Out of Reach: Ensure the medication is kept out of reach of children.
Summary: Amoxiclav (Acinet) 375mg Tablets provide effective treatment for various bacterial infections. It’s essential to follow the prescribed dosage and complete the full course of treatment to ensure the infection is adequately treated and to prevent the development of antibiotic resistance. Always consult a healthcare provider before starting any new medication.
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