Description
DICLO DENK 100MG RECTAL SUPPOSITORY contains diclofenac sodium 100mg, a potent non-steroidal anti-inflammatory drug (NSAID) formulated for rectal administration. It is used for the relief of pain, inflammation, and swelling associated with various acute and chronic musculoskeletal and inflammatory conditions.
Indications:
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Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis
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Acute musculoskeletal injuries (sprains, strains, back pain)
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Postoperative or post-traumatic pain
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Menstrual pain (dysmenorrhea)
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Migraine attacks
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Patients unable to take oral NSAIDs due to nausea, vomiting, or swallowing difficulties
Mechanism of Action:
Diclofenac works by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, which are involved in the production of prostaglandins—substances responsible for pain, inflammation, and fever. The rectal route allows for fast systemic absorption, bypassing the gastrointestinal tract, which may be beneficial for patients with gastric sensitivity or nausea.
Administration and Dosage:
The suppository is intended for rectal use only. One 100mg suppository is typically administered once daily, or as directed by a physician. It should be inserted gently into the rectum, preferably after a bowel movement for optimal absorption.
Precautions:
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Not recommended in individuals with known NSAID allergies, active gastrointestinal ulcers, or severe hepatic, renal, or cardiac impairment
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Use with caution in elderly patients and those with cardiovascular risk factors
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Should not be used in the last trimester of pregnancy
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Regular monitoring is advised during prolonged therapy
Common Side Effects:
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Local irritation or discomfort at the site of insertion
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Abdominal cramps, diarrhea (rare)
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Headache, dizziness
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Nausea or indigestion
DICLO DENK 100MG SUPPOSITORY offers fast and effective pain and inflammation relief, especially when oral administration is not suitable.
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