Description
DICLO DENK INJECTION 75MG/3ML 1’S is a parenteral formulation of diclofenac sodium, a non-steroidal anti-inflammatory drug (NSAID) indicated for the rapid relief of moderate to severe pain and inflammation. Each 3ml ampoule contains 75mg of diclofenac, intended for intramuscular (IM) administration by a healthcare professional.
Indications:
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Acute musculoskeletal pain (e.g., back pain, sprains, strains)
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Postoperative or post-traumatic pain
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Renal colic
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Acute flare-ups of rheumatic conditions such as rheumatoid arthritis or ankylosing spondylitis
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Pain management when oral or rectal routes are not suitable
Mechanism of Action:
Diclofenac inhibits cyclooxygenase (COX-1 and COX-2) enzymes, leading to reduced synthesis of prostaglandins—key mediators of inflammation, pain, and fever. By reducing prostaglandin production, diclofenac provides quick and effective anti-inflammatory and analgesic effects.
Dosage & Administration:
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The recommended adult dose is 75mg once daily, injected deep into the upper outer quadrant of the gluteal muscle.
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In severe cases, a second injection may be administered after a few hours in the opposite gluteal muscle.
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Use should be limited to short-term treatment (1–2 days), with a transition to oral therapy as soon as possible.
Precautions:
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Not recommended for patients with a history of NSAID-induced gastrointestinal bleeding, peptic ulcers, or severe cardiac, hepatic, or renal impairment
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Use with caution in elderly patients or those with cardiovascular risk factors
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Contraindicated during the third trimester of pregnancy
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Should only be administered by trained medical personnel
Common Side Effects:
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Injection site pain or irritation
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Nausea, dizziness
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Elevated liver enzymes (with repeated use)
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Rarely: gastrointestinal bleeding, allergic reactions
DICLO DENK INJ 75MG offers fast-acting pain relief in acute settings, particularly where oral administration is not feasible.
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