Description
Gliclazide (GLIZ) MR 60/1000mg Tablets (30’s)
Gliclazide MR 60/1000mg is a modified-release tablet combining Gliclazide 60mg and Metformin Hydrochloride 1000mg. It is designed for effective management of type 2 diabetes mellitus through complementary mechanisms to maintain blood glucose control.
Key Features:
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Gliclazide (60mg, modified release): A sulfonylurea that stimulates pancreatic insulin secretion, with controlled release for prolonged effect and reduced hypoglycemia risk.
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Metformin (1000mg): A biguanide that decreases hepatic glucose production and enhances insulin sensitivity.
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Convenient once or twice daily dosing with improved gastrointestinal tolerability.
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Helps achieve sustained glycemic control with reduced fluctuations.
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Supports weight neutrality and has cardiovascular benefits.
Indications:
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For adult patients with type 2 diabetes mellitus inadequately controlled with diet and exercise alone.
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Suitable for patients who require combination therapy with sulfonylurea and metformin.
Dosage & Administration:
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Take with meals to reduce gastrointestinal side effects.
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Dosage individualized according to patient response and tolerance.
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Regular monitoring of blood glucose and kidney function is recommended.
Precautions:
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Not intended for type 1 diabetes or diabetic ketoacidosis.
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Use cautiously in patients with renal or hepatic impairment.
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Monitor for symptoms of hypoglycemia and lactic acidosis.
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Inform healthcare providers about all concurrent medications.
Possible Side Effects:
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Hypoglycemia (low blood sugar)
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Gastrointestinal discomfort (nausea, diarrhea)
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Weight gain (possible with sulfonylurea)
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Rare: lactic acidosis, allergic reactions
Storage:
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Store in a cool, dry place below 25°C.
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Keep out of reach of children.
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