ACNOTREN 10MG 30’S

ACNOTREN 10 mg Capsules (30’s) contain Isotretinoin 10 mg, a potent oral retinoid for severe, treatment-resistant acne (e.g., nodular or cystic acne) .

🧪 Key Information

• Composition: Isotretinoin 10 mg per softgel capsule (pharm.cals.am)
• Mechanism of Action: Reduces sebum production, shrinks sebaceous glands, normalises keratinisation, and exerts anti-inflammatory effects (Dwaey)

✅ Indications

• Severe nodular or cystic acne unresponsive to standard therapy (antibiotics, topicals)
• Acne that may cause permanent scarring (WebMD, Dwaey)

⚙️ Dosage & Administration

• Typical starting dose: 0.5 mg/kg/day, often split into two doses
• Possible adjustment: Up to 1–2 mg/kg/day based on response and tolerance (Vinmec International Hospital, Dwaey)
• Duration: 16–24 weeks (4–6 months) with effects continuing for up to 8 weeks post-treatment (nhs.uk)
• Instructions: Take with food, swallow whole with a full glass of water (Vinmec International Hospital)

⚠️ Safety & Precautions

• Teratogenicity: Strict contraception required in women of childbearing potential; negative pregnancy tests before, during, and after therapy (mayoclinic.org)
• Common side effects: Dry skin, lips, eyes, nosebleeds (Drugs.com)
• Serious risks: Elevated liver enzymes, cholesterol, triglycerides; mood changes; headaches; gastrointestinal or visual disturbances

🔍 Monitoring Requirements

• Baseline and periodic tests: liver function, lipids
• Regular clinical follow-up for side effects, mental health, pregnancy status in women

ACNOTREN is one of the most effective treatments available for severe acne when used under close medical supervision.