New

Medicine

CELENTA 200 CAPS 10’S

Login to view prices

SKU:

RADC011

Description

CELENTA 200mg Capsules (10’s) contain Celecoxib, a selective COX-2 inhibitor nonsteroidal anti-inflammatory drug (NSAID) formulated as oral capsules. Manufactured by Incepta Pharmaceuticals Ltd., CELENTA is used to alleviate pain and inflammation associated with various musculoskeletal and inflammatory conditions.

Indications:
CELENTA Capsules are indicated for:

• Osteoarthritis

• Rheumatoid arthritis

• Ankylosing spondylitis

• Dysmenorrhea (painful menstruation)

• Acute pain

• Familial adenomatous polyposis (FAP), for the regression and prevention of colorectal adenomatous polyps

Dosage and Administration:

• Osteoarthritis: 200 mg/day as a single dose or in two divided doses. May increase to 200 mg twice daily if necessary.

• Rheumatoid arthritis: 100–200 mg twice daily.

• Dysmenorrhea: Initially, 400 mg followed by 200 mg if necessary on the first day. Maintenance: 200 mg twice daily.

• Ankylosing spondylitis: Initially, 200 mg/day as a single dose or in two divided doses. May increase to 400 mg/day after 6 weeks.

• Familial adenomatous polyposis (FAP): 400 mg twice daily with food.

Contraindications:

• Hypersensitivity to Celecoxib, other NSAIDs, or sulfonamides

• Severe hepatic impairment

• Severe heart failure

• Inflammatory bowel disease

• Peptic ulcer

• Renal impairment (creatinine clearance <30 mL/min)

• Pregnancy and lactation

Precautions:

• History of gastrointestinal bleeding

• Renal/hepatic insufficiency

• Asthma or allergic disorders

• Hypertension

• Monitor hemoglobin or hematocrit levels for signs of anemia

• History of cerebrovascular disease or ischemic heart disease

Side Effects:
Common side effects include:

• Headache (10–16%)

• Hypertension (13%)

• Dyspepsia (8.8%)

• Upper respiratory tract infection (8.1%)

• Arthralgia (7%)

• Cough (7%)

• Vomiting (6%)

• Diarrhea (5.6%)

• Gastroesophageal reflux (5%)

• Sinusitis (5%)

• Abdominal pain (4.1%)

• Nausea (3.5%)

• Back pain (2.8%)

• Insomnia (2.3%)

• Pharyngitis (2.3%)

• Flatulence (2.2%)

• Rash (2.2%)

• Dizziness (2%)

• Peripheral edema (2%)

Serious adverse effects may include:

• Anemia

• Erythema multiforme

• Exfoliative dermatitis

• Hepatitis

• Jaundice

• Stevens-Johnson syndrome

• Toxic epidermal necrolysis

Mode of Action:
Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor that reduces mediators of pain and inflammation by inhibiting prostaglandin synthesis via COX-2.

Storage:
Store below 25°C in a dry place. Keep capsules in their original packaging, protected from moisture and light. Keep out of reach of children.