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CLEXANE INJ 40MG 2’S

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SKU:

SANC002

Description

CLEXANE INJECTION 40MG (2 x 0.4ML) – Product Description

Clexane 40mg Injection is a low molecular weight heparin (LMWH) containing enoxaparin sodium. It is primarily used for the prevention and treatment of thromboembolic disorders, including deep vein thrombosis (DVT), pulmonary embolism (PE), and as an adjunct in the management of unstable angina and non-ST elevation myocardial infarction (NSTEMI).

Key Features & Benefits:

• Mechanism of Action: Enoxaparin enhances the activity of antithrombin III, leading to the inhibition of clotting factors Xa and IIa (thrombin), thereby reducing the formation of harmful blood clots.

• Indications:

  • DVT Prophylaxis: Prevention of DVT in patients undergoing abdominal, hip, or knee surgeries, and in those with restricted mobility due to acute illness.

  • DVT & PE Treatment: Management of existing DVT with or without PE.

  • Unstable Angina & NSTEMI: Used in combination with aspirin for the prevention of ischemic complications.

• Dosage:

  • DVT Prophylaxis: 40mg subcutaneously once daily.

  • DVT & PE Treatment: 1mg/kg subcutaneously every 12 hours, or 1.5mg/kg once daily.

  • Unstable Angina/NSTEMI: 1mg/kg subcutaneously every 12 hours, in conjunction with aspirin.

Administration:

• Administered via subcutaneous injection, typically in the anterolateral or posterolateral abdominal wall.

• Rotate injection sites to minimize discomfort and tissue irritation.

• Do not massage the injection site post-administration.

Precautions:

• Contraindications: Known hypersensitivity to enoxaparin or heparin, active bleeding disorders, recent surgery involving the eye, brain, or spinal cord, and severe thrombocytopenia.

• Use with Caution: In patients with renal impairment, active gastrointestinal ulcers, or a history of heparin-induced thrombocytopenia.

• Pregnancy & Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.

Side Effects:

• Common: Injection site reactions (pain, redness, bruising), minor bleeding (e.g., gingival bleeding, epistaxis).

• Serious (Rare): Major bleeding events (intracranial, gastrointestinal), heparin-induced thrombocytopenia (HIT), allergic reactions (rash, urticaria), hyperkalemia.

Storage:

• Store at room temperature, away from light and moisture.

• Do not freeze. Discard any unused portion after administration.

Note: This medication should be administered under the supervision of a healthcare professional. Regular monitoring of platelet counts and renal function may be required during treatment. Always follow the dosing regimen prescribed by your healthcare provider.