Description
DICLO DENK TABS 100MG RETARD 100’S is a sustained-release formulation of diclofenac sodium, an effective non-steroidal anti-inflammatory drug (NSAID) used for long-term management of pain and inflammation. Each tablet contains 100mg of diclofenac sodium and is designed for once-daily oral administration, ensuring prolonged therapeutic effect and improved patient compliance.
Indications:
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Rheumatoid arthritis
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Osteoarthritis
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Ankylosing spondylitis
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Chronic musculoskeletal disorders
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Persistent low back pain
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Postoperative or post-traumatic pain
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Pain due to dental or orthopedic procedures
Mechanism of Action:
Diclofenac works by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, thereby reducing the synthesis of prostaglandins responsible for inflammation, pain, and fever. The retard (sustained-release) formulation ensures gradual release of the drug over time, providing consistent pain relief throughout the day and reducing the need for multiple daily doses.
Dosage & Administration:
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Usual adult dose: 100mg once daily
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Should be taken with food to minimize gastrointestinal side effects
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Tablets should be swallowed whole—do not crush or chew
Precautions:
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Not recommended for patients with active peptic ulcers, gastrointestinal bleeding, or severe heart, liver, or kidney disorders
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Use with caution in patients with cardiovascular risk factors or a history of NSAID sensitivity
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Avoid use during the third trimester of pregnancy
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Prolonged use requires periodic monitoring of liver and kidney function, as well as blood pressure
Common Side Effects:
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Nausea, abdominal discomfort
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Indigestion or bloating
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Headache, dizziness
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Elevated liver enzymes (with long-term use)
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Rare: gastrointestinal bleeding or allergic reactions
DICLO DENK 100MG RETARD TABS offer reliable, once-daily relief from chronic inflammatory pain, ideal for patients requiring sustained NSAID therapy.
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