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LABETOLOL (PRESOLOL) 200MG TABS 100’S

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GENL229

Description

Presolol 200 mg Tablets (100’s pack) contain Labetalol Hydrochloride 200 mg, a dual-action antihypertensive that blocks both alpha‑ and beta‑adrenergic receptors to help lower blood pressure effectively

Key Uses:

  • Management of mild, moderate, and severe hypertension

  • Treatment of hypertension during pregnancy

  • Control of angina when coexisting with hypertension

How It Works:

Labetalol reduces heart rate and blood vessel constriction by blocking β and α₁ receptors, leading to decreased peripheral resistance and improved cardiac output.

Dosage:

  • Initial dose: 100 mg twice daily with food

  • Typical maintenance: Increases of 100 mg twice daily every 1–2 weeks, often maintained at 200 mg twice daily

  • Higher doses: For refractory cases, daily doses up to 800 mg (divided) or up to 2,400 mg in severe hypertension

Precautions:

  • Avoid in patients with asthma, COPD, severe bradycardia, heart block, cardiogenic shock, or uncontrolled heart failure. Not suitable during first trimester of pregnancy.

  • Use with caution in liver impairment—rare reversible liver damage has been reported. Monitor liver function during therapy.Medex

  • Do not discontinue abruptly—taper gradually to prevent rebound hypertension or angina.

Common Side Effects:

  • Dizziness, headache, fatigue, nausea, or light-headedness

  • Rare but serious events include bradycardia, orthostatic hypotension, bronchospasm, and hepatic dysfunction

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