Medicine

LINCOZED INJ 300MG/ML 2ML 1’S

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SKU:

GENL034

Description

LINCOZED INJECTION 300MG/ML (2ML) – 1 VIAL

Product Overview:
Lincozed 300mg/2mL Injection is a sterile solution containing 300mg/mL of lincomycin hydrochloride, formulated for intramuscular (IM) or intravenous (IV) administration. This potent antibiotic is used to treat serious infections caused by susceptible Gram-positive bacteria, including those resistant to penicillin.

Mechanism of Action:
Lincozed inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, effectively halting bacterial growth. It is particularly useful in patients with penicillin allergies or when penicillin therapy is ineffective.

Indications:
Lincozed is indicated for the treatment of various bacterial infections, including:

• Respiratory tract infections (e.g., pneumonia)
• Skin and soft tissue infections
• Bone and joint infections
• Intra-abdominal infections
• Dental infections

Dosage and Administration:

• Adults:
  • Intramuscular (IM): 600mg every 12 to 24 hours.
  • Intravenous (IV): 600 to 1000mg every 8 to 12 hours; not to exceed 8g/day.
• Administration: Administer under the supervision of a healthcare professional. The dosage may vary based on the severity of the infection and patient response.

Contraindications:

• Hypersensitivity to lincomycin or any component of the formulation.
• Use in neonates (≤1 month) due to the presence of benzyl alcohol.

Precautions:

• Serotonin Syndrome: Risk increases when used with serotonergic drugs. Monitor for symptoms such as agitation, hallucinations, tachycardia, and changes in blood pressure.
• Myelosuppression: Prolonged use may lead to thrombocytopenia, anemia, or leukopenia. Regular blood counts are recommended during therapy.
• Lactic Acidosis: Rare but serious side effect; discontinue if symptoms occur.

Side Effects:
Common side effects may include:

• Diarrhea
• Nausea and vomiting
• Abdominal pain
• Rash
• Itching
• Oral or vaginal fungal infections (e.g., thrush)

Serious side effects are rare but may include:

• Severe allergic reactions (e.g., anaphylaxis)
• Liver dysfunction
• Blood disorders (e.g., neutropenia)
• Severe gastrointestinal symptoms

Storage:
Store at room temperature, away from moisture and heat. Keep out of reach of children.

Note:
Lincozed Injection is available by prescription only. Use under the supervision of a healthcare professional.